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It is a congenital hand disorder and the prevalence of camptodactyly is between 0. Clinically, camptodactyly is usually divided into three types.
Type I is the most common, and camptodactyly is limited to the fifth finger. The abnormalities become apparent during infancy and affect boys and girls equally.
Type II does not become apparent until preadolescence ages 7 to 11 years and affect girls more. The abnormality usually does not improve and may develop to severe flexion deformity.
Type III is the most severe type involving multiple digits of both upper extremities, and is usually associated with a variety of syndromes [ 3 ]. Camptodactyly may also be simplified classified as nonsyndromic camptodactyly an isolated autosomal dominant anomaly, Type I and Type II and syndromic camptodactyly associated with other different manifestations, Type III [ 4 ].
More than 60 distinct types of syndromic camptodactyly have been described in the literature, and camptodactyly phenotype has been observed in carriers with chromosomal abnormalities or gene mutations, including dup 15 q24q RH mutation [ 4 — 9 ]. Only one disease locus CAMPD1 for nonsyndromic camptodactyly with knuckle pads was mapped to chromosome 3q Here, we report a large Chinese kindred with typical features of isolated fifth finger camptodactyly.
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